Background and Objectives: Mulberry (Morus alba) has high antioxidants, including flavonoids and 1-deoxynojirimycin (DNJ) which is an alpha-glucosidase inhibitor to reduce blood sugar levels. Previous studies have shown that leaves of mulberry (Buriram 60 strain) had higher DNJ than others. The purpose of this study was to investigate the effect of consumption of mulberry (Buriram 60) tea on blood glucose and satiety levels.
Methods: This was a randomized crossover study. Twelve healthy volunteers age 20-23 years old in Burapha University participated. There were control group and intervention group which had the same subjects but they were washed out between two groups for 1 week. Subjects in intervention group consumed mulberry leaf tea (Buriram 60 strain) while subjects in control group consumed warm water after consumption of glucose solution for 15 minutes. Blood glucose, satiety, blood pressure, heart rate, body temperature, and electrocardiography were measured before (0 min) and after the consumptions at 30, 60, 90 and 120 min.
Results: Blood glucose level in the intervention group was significantly lower than in the control group at 30 min (p=0.039). Standard deviation of normal-to-normal intervals (SDNN) in the intervention group was significantly higher than in the control group at 120 min (p=0.045). The levels of satiety, blood pressure, heart rate, and body temperature between groups were not significantly different.
Conclusion: This study suggested that consumption of mulberry tea (Buriram 60 strain) after consumption of glucose solution reduces blood sugar level and enhances parasympathetic activity in healthy subjects.