Background and Objective: Colon cancer is an aggressive disease and patients have high risk of mortality. Most of patients had abnormal symptoms of disease before they came to meet doctors. The surgical treatment of colon cancer might increase survival rate of patients. Therefore, the objective of this study was to compare survival rate of colon cancer between stage II and III after surgical treatment.
Methods: This study was a retrospective cohort study and all data were collected from medical records. New cases of stage II and III of colorectal cancer patients who were undergone surgery at Roi Et hospital during January 1, 2013 to December 31, 2015 were included in this study. The vital status of patients was followed up until they were death or it had reaches the end of this study (March 31, 2016). Descriptive statistics, Kaplan-Meier method and Log-rank test were used to analyze data.
Results: There were 220 new cases of patients who were newly diagnosed as stage II and III colon cancer and the majority of these patients were female (51.36 %) with mean of age at 62.49 ± 12.60 years. The total follow-up time was 4,138 person-months and the overall median survival time was 30.4 months. There were 101 cases were death and the mortality rate was 2.44 per 100 person-months. The median survival time of 79 cases with colon cancer stage II was 52.6 months and the cumulative 6-month, 1-, 2- and 3-year survival rate was 87.09%, 74.82%, 63.95% and 55.16 %, respectively. The median survival time of 141 cases with colon cancer stage III was 17.8 months with cumulative 6-month, 1-, 2- and 3-year survival rate was 82.14%, 78.46%, 66.66% and 32.25 %, respectively.
Conclusion: The median survival time of stage II colon cancer patients after surgery was longer than patients with colon cancer stage III and the cumulative 3-year survival rate of patients with colon cancer stage II was higher than patients with colon cancer stage III.